GPO α THAL IC Strip Test
The GPO α THAL IC Strip Test is a qualitative, lateral flow immunoassay for the screening of various types of alpha (α) thalassemia trait in whole blood. As the blood test sample diffuses through the absorbent test strip, the labeled antibody-dye conjugate binds to the Hb Bart's in the specimen forming an antibody-antigen complex. This complex binds to the anti Hb Bart's antibody in the test line and expresses a colored band. The absence of a colored band in the test region indicates a negative result. The reaction mixture continues flowing through the absorbent device past the test and control lines. Unbound conjugate binds to the reagents in the control line, producing a pink color band, demonstrating that the reagents and test strip are functioning correctly.
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